Multiple Sclerosis Pathogenesis

Dr. Mohammad Saeed was invited to talk on the “Multiple Sclerosis Pathogenesis” at the Aga Khan University (AKU). The event was organized by the Multiple Sclerosis Research and Education Forum at AKU led by Professor Mohammad Wasay (Neurologist). The day-long Multiple Sclerosis (MS) workshop was part of a nation-wide effort to train medical and paramedical staff in MS care. The presentation by Dr. Mohammad Saeed is attached below.

Early diagnosis and treatment is key to preventing neurological damage to patients. At ImmunoCure Laboratory rapid and efficient tests of the highest quality are available for a vast array of autoimmune diseases, including those affecting the nervous system. For demyelinating diseases such as Multiple Sclerosis, Neuromyelitis optica (NMO) and NMO spectrum disorders (NMOSD) ImmunoCure offers Immunoflourescence based testing for Aquaporin-4 (AQP4) antibody and myelin oligodendrocyte glycoprotein (MOG) antibody. AQP4-Ab is present in 80% of NMO while MOG-Ab is present in ~ 30% of NMOSD negative for AQP4-Ab. MOG-Ab is also present in 30-40% of acute disseminated encephalomyelitis (ADEM) and 5% of MS patients (1). These novel tests are helping Neurologists across Pakistan in making accurate and early diagnosis of autoimmune neurological diseases. Early diagnosis followed by rapid treatment, often with the latest biologic medications, has a major impact on reducing complications of these devastating diseases which were formerly thought to be incurable.

1. Peschl et al. (2017). Front Immunol. PMID: 28533781

Dr. Mohammad Saeed Multiple Sclerosis Presentation

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